952024-11-2Relevant academic research and scientific papers
Synthesis of 1-arylmethyl-2-(2-cyanoethyl)aziridines and their rearrangement into novel 2-(aminomethyl)cyclopropanecarbonitriles
D'Hooghe, Matthias,Vervisch, Karel,De Kimpe, Norbert
, p. 7329 - 7332 (2008/02/11)
(Chemical Equation Presented) 1-Arylmethyl-2-(bromomethyl)aziridines were transformed into novel 2-(2-cyanoethyl)aziridines upon treatment with α-lithiated trimethylsilylacetonitrile in THF in an efficient and straightforward approach. The latter aziridin
