952117-05-4Relevant academic research and scientific papers
Dynamic kinetic asymmetric allylic amination and acyl migration of vinyl aziridines with imido carboxylates
Trost, Barry M.,Fandrick, Daniel R.,Brodmann, Tobias,Stiles, Dylan T.
, p. 6123 - 6125 (2008/09/16)
(Chemical Equation Presented) An atom-economical method has been developed for the preparation of chiral vicinal diamines through a dynamic kinetic asymmetric allylic amination and acyl-group migration of vinyl aziridines with imido carboxylates. Application of the asymmetric transformation enabled the concise synthesis of the azepane core 1 of (+)-balanol and its syn analogue.
