952139-83-2

Upstream product

• 858108-84-6 C-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanol 
• 124-63-0 methanesulfonyl chloride 
• 148968-89-2 2-azido-3,4,6-tri-O-benzyl-2-deoxy-D-mannopyranose 
• 858363-68-5 1-C-(2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-mannopyranosyl)-allene 
• 858108-82-4 C-(2-azido-3,4,6-tri-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanol 

Downstream Products

• 858108-88-0 N-((2S,3S,4R,5S,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-iodomethyl-tetrahydro-pyran-3-yl)-acetamide 
• 858108-90-4 dimethyl C-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanephosphonate 
• 858109-06-5 [N-(benzyloxycarbonyl)aminopropyl (2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-mannopyranosidyl)]methyl C-(2-acetamido-3,4-di-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanephosphonate 
• 952139-86-5 [N-(benzyloxycarbonyl)aminopropyl (2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-mannopyranosidyl)]methyl C-(2-acetamido-6-O-acetyl-3,4-di-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanephosphonate 
• 858109-04-3 [N-(benzyloxycarbonyl)aminopropyl (2-acetamido-3,4-di-O-benzyl-2-deoxy-β-D-mannopyranosidyl)]methyl C-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-α-D-mannopyranosyl)methanephosphonate 

Relevant academic research and scientific papers

Synthesis and biological evaluation of phosphono analogues of capsular polysaccharide fragments from Neisseria meningitidis A

Neisseria meningitidis type A (MenA) is a Gram-negative encapsulated bacterium that may cause explosive epidemics of meningitis, especially in the sub-Saharan region of Africa. The development and manufacture of an efficient glycoconjugate vaccine against

Synthesis of the phosphono analogue of the dimeric subunit of Neisseria meningitidis type A capsular polysaccharide

The development of a glycoconjugate vaccine against N. meningitidis type A bacterium is greatly hampered by the chemical lability of the phosphodiester bridges joining the N-acetyl mannosamine repeating units of its capsular polysaccharide. We describe th