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95218-34-1

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95218-34-1 Usage

General Description

N-(2,4-Dimethoxybenzyl)glycine ethyl ester is a chemical compound that is often used in the field of organic synthesis. It is a derivative of glycine, an amino acid, and is typically produced through the reaction of 2,4-dimethoxybenzyl chloride with glycine ethyl ester. N-(2,4-Dimethoxybenzyl)glycine ethyl ester has been studied for its potential use in pharmaceutical applications, as it may have therapeutic effects on the central nervous system. Additionally, it has also been investigated for its potential use as a building block in the synthesis of more complex organic molecules. Overall, N-(2,4-Dimethoxybenzyl)glycine ethyl ester is a versatile chemical that has potential applications in both the pharmaceutical and organic synthesis industries.

Check Digit Verification of cas no

The CAS Registry Mumber 95218-34-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,2,1 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 95218-34:
(7*9)+(6*5)+(5*2)+(4*1)+(3*8)+(2*3)+(1*4)=141
141 % 10 = 1
So 95218-34-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H19NO4/c1-4-18-13(15)9-14-8-10-5-6-11(16-2)7-12(10)17-3/h5-7,14H,4,8-9H2,1-3H3

95218-34-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-[(2,4-dimethoxyphenyl)methylamino]acetate

1.2 Other means of identification

Product number -
Other names N-2,4-dimethoxybenzyl glycine ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:95218-34-1 SDS

95218-34-1Downstream Products

95218-34-1Relevant articles and documents

AKT INHIBITOR

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Paragraph 0323-0325, (2021/12/18)

The present invention discloses an AKT inhibitor, and specifically relates to a compound represented by formula I or a pharmaceutically acceptable salt thereof. The present invention further provides a preparation method thereof, and the use thereof in prevention and/or treatment of a disease mediated by AKT protein kinase.

BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT

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Paragraph 1442, (2018/07/05)

This invention relates to benzodiazepine derivatives, compositions comprising therapeutically effective amounts of those benzodiazepine derivatives and methods of using those derivatives or compositions in treating cognitive impairment associated with central nervous system (CNS) disorders. In particular, it relates to the use of a α5-containing GABAA receptor agonist (e.g., a α5-containing GABAA receptor positive allosteric modulator) as described herein in treating cognitive impairment associated with central nervous system (CNS) disorders in a subject in need or at risk thereof, including, without limitation, subjects having or at risk for age-related cognitive impairment, Mild Cognitive Impairment (MCI), amnestic MCI (aMCI), Age-Associated Memory Impairment (AAMI), Age Related Cognitive Decline (ARCD), dementia, Alzheimer's Disease(AD), prodromal AD, post traumatic stress disorder (PTSD), schizophrenia, bipolar disorder, amyotrophic lateral sclerosis (ALS), cancer-therapy-related cognitive impairment, mental retardation, Parkinson's disease (PD), autism spectrum disorders, fragile X disorder, Rett syndrome, compulsive behavior, and substance addiction. It also relates to the use of a α5-containing GABAA receptor agonist (e.g., a α5-containing GABAA receptor positive allosteric modulator) as described herein in treating brain cancers (including brain tumors, e.g., medulloblastomas), and cognitive impairment associated therewith.

Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries

Craven, Philip,Aimon, Anthony,Dow, Mark,Fleury-Bregeot, Nicolas,Guilleux, Rachel,Morgentin, Remy,Roche, Didier,Kalliokoski, Tuomo,Foster, Richard,Marsden, Stephen P.,Nelson, Adam

supporting information, p. 2629 - 2635 (2015/01/30)

The design, synthesis and decoration of six small molecule libraries is described. Each library was inspired by structures embedded in the framework of specific alkaloid natural products. The development of optimised syntheses of the required molecular scaffolds is described, in which reactions including Pd-catalysed aminoarylation and diplolar cycloadditions have been exploited as key steps. The synthesis of selected exemplar screening compounds is also described. In five cases, libraries were subsequently nominated for production on the basis of the scope and limitations of the validation work, as well as predicted molecular properties. In total, the research has led to the successful synthesis of >2500 novel alkaloid-like compounds for addition to the screening collection (the Joint European Compound Library, JECL) of the European Lead Factory.

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