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2-(trifluoromethyl)quinoline-6-carboxylic acid is a quinoline derivative with the molecular formula C11H6F3NO2, featuring a trifluoromethyl group and a carboxylic acid group. It is a significant chemical compound in the pharmaceutical industry, known for its potential as a building block in the synthesis of new drugs and biologically active compounds. The trifluoromethyl group enhances the potency and metabolic stability of drug candidates, while the quinoline core, common in natural products and pharmaceuticals, contributes to its versatility. The carboxylic acid group allows for further chemical modifications, making 2-(trifluoromethyl)quinoline-6-carboxylic acid adaptable for various applications in drug development.

952182-51-3

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952182-51-3 Usage

Uses

Used in Pharmaceutical Industry:
2-(trifluoromethyl)quinoline-6-carboxylic acid is used as a building block for the synthesis of new drugs and biologically active compounds. Its trifluoromethyl group increases the potency and metabolic stability of drug candidates, making it a valuable component in the development of pharmaceuticals with improved therapeutic properties.
Used in Drug Development:
2-(trifluoromethyl)quinoline-6-carboxylic acid is used as a precursor in the creation of novel drug candidates. The presence of the carboxylic acid group provides flexibility for chemical modifications, enabling the compound to be tailored for specific therapeutic purposes, thus broadening its applications across various therapeutic areas.
Used in Medicinal Chemistry:
2-(trifluoromethyl)quinoline-6-carboxylic acid is utilized as a key intermediate in medicinal chemistry for the design and synthesis of new chemical entities. Its structural features facilitate the exploration of new pharmacological spaces and the optimization of drug-like properties, contributing to the advancement of drug discovery efforts.
Used in Drug Synthesis:
2-(trifluoromethyl)quinoline-6-carboxylic acid is employed as a synthetic intermediate in the preparation of complex drug molecules. Its unique combination of functional groups allows for the construction of diverse chemical scaffolds, which can be further elaborated to achieve desired pharmacological profiles and therapeutic effects.

Check Digit Verification of cas no

The CAS Registry Mumber 952182-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,2,1,8 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 952182-51:
(8*9)+(7*5)+(6*2)+(5*1)+(4*8)+(3*2)+(2*5)+(1*1)=173
173 % 10 = 3
So 952182-51-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H6F3NO2/c12-11(13,14)9-4-2-6-5-7(10(16)17)1-3-8(6)15-9/h1-5H,(H,16,17)

952182-51-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(Trifluoromethyl)quinoline-6-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-(trifluoromethyl)quinoline-6-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:952182-51-3 SDS

952182-51-3Relevant academic research and scientific papers

AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME

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Page/Page column 43, (2012/04/18)

Compounds are disclosed that have a formula represented by the following: Formula (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

SUBSTITUTED BICYCLOCARBOXYAMIDE COMPOUNDS

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Page/Page column 66, (2008/12/05)

This invention provides a compound of the formula (I). These compounds are useful for the treatment of disease conditions caused by overactivation of the VR1 receptor such as pain, or the like in mammal. This invention also provides a pharmaceutical composition comprising the above compound.

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