952391-91-2

Upstream product

• 15221-61-1 2-(4-bromophenyl)-N,N-dimethylethan-1-amine 
• 114369-15-2 2-(4-bromophenyl)ethyl methanesulfonate 
• 4654-39-1 4-bromophenethanol 
• 106-37-6 1.4-dibromobenzene 

Downstream Products

• 952301-53-0 bis{4-[(N,N-dimethylamino)ethyl]phenyl}phosphine tris(borane) 

Relevant academic research and scientific papers

Traceless Staudinger acetylation of azides in aqueous buffers

In this paper, we demonstrate the applicability of water-soluble p-dimethylaminoethyl substituted phosphinomethanethiol in acetyl transfer reactions by the traceless Staudinger ligation with unprotected *-azido lysine containing peptides in aqueous buffer systems. Additionally, we present an improved synthesis pathway for the water-soluble phosphinothiol linkers requiring less steps in a comparable overall yield in comparison to previously published protocols.