952527-75-2

Upstream product

• 170456-80-1 3-iodo-1-tosyl-1-indole 
• 1066-54-2 trimethylsilylacetylene 
• 120-72-9 indole 
• 98-59-9 p-toluenesulfonyl chloride 
• 26340-47-6 3-Iodo-1H-indole 

Downstream Products

• 765914-04-3 3-ethynyl-1-(toluene-4-sulfonyl)-1H-indole 
• 13640-26-1 pimprinine 
• 952527-64-9 3-cyclohept-1-enyl-4-(1-tosyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione 
• 952527-62-7 3-cyclohex-1-enyl-4-(1-tosyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione 
• 952527-60-5 3-cyclopent-1-enyl-4-(1-tosyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione 
• 952527-63-8 3-cyclohept-1-enyl-1-(4-nitro-phenyl)-4-[1-(toluene-4-sulphonyl)-1H-indol-3-yl]-pyrrole-2,5-dione 
• 952527-61-6 3-cyclohex-1-enyl-1-(4-nitro-phenyl)-4-[1-(toluene-4-sulphonyl)-1H-indol-3-yl]-pyrrole-2,5-dione 
• 952527-59-2 3-cyclopent-1-enyl-1-(4-nitro-phenyl)-4-[1-(toluene-4-sulphonyl)-1H-indol-3-yl]-pyrrole-2,5-dione 
• 952527-39-8 3-cycloheptylidene-2-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid methyl ester 
• 952527-38-7 3-cyclohexylidene-2-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]acrylic acid methyl ester 
• 952527-77-4 carbonic acid methyl ester 1-[1-(toluene-4-sulfonyl)-1H-indol-3-ylethynyl]-cyclohexyl ester 
• 952527-37-6 3-cyclopentylidene-2-[1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid methyl ester 
• 952527-76-3 carbonic acid methyl ester 1-[1-(toluene-4-sulfonyl)-1H-indol-3-ylethynyl]-cyclopentyl ester 

Relevant academic research and scientific papers

Gold-catalyzed oxazoles synthesis and their relevant antiproliferative activities

Nine 5-aryl-2-methyloxazole derivatives were synthesized via gold-catalyzed alkyne oxidation. All of the compounds have been screened for their antiproliferative activities against MCF-7 cell (human breast carcinoma), A549 cell (human lung carcinoma) and

Cobalt-Catalyzed Hydroalkynylation of Vinylaziridines

Transition metal-catalyzed hydroalkynylation reactions are efficient transformations allowing the straightforward formation of functionalized alkynes. Therein, we disclose the cobalt-catalyzed hydroalkynylation of vinylaziridines giving rise to both linea

Pd/Cu-Catalyzed Vinylation of Terminal Alkynes with (2-Bromoethyl)diphenylsulfonium Triflate

The potential of (2-bromoethyl)diphenylsulfonium triflate to be a powerful vinylation reagent was determined by the Sonogashira cross-coupling reactions with terminal alkynes. The vinylation proceeded smoothly at 25 °C under Pd/Cu catalysis to afford a variety of 1- and 2-unsubstituted 1,3-enynes in moderate to excellent yields. This protocol represents the first application of (2-haloethyl)diphenylsulfonium triflate as a CH═CH2 transfer source in organic synthesis.

A new protocol for nickel-catalysed regio- and stereoselective hydrocyanation of allenes

Regio- and stereoselective hydrocyanation under nickel catalysis is described. This report shows that allenyl C-C double bonds are discriminated and converted to the corresponding carbonitriles as a single product. The key functionalities for achieving high regio- and stereocontrol are aryl and cyclopropyl groups in the substrates. This journal is

Efficient synthesis of maleimides and carbazoles via Zn(OTf) 2-catalyzed tandem annulations of Lsonitriles and allenic esters

Lewis acid Zn(OTf)2-catalyzed tandem annulations of isonitriles and allenic esters which lead to efficient and flexible syntheses of a range of biologically significant maleimides and carbazoles and related compounds are reported. A mechanistic rationale is proposed to account for the observed reactivity.