952600-52-1Relevant academic research and scientific papers
A novel synthetic protocol for the synthesis of pulvinones, and naturally occurring Aspulvinone E, molecules of medicinal interest
Prousis, Kyriakos C.,Katsamakas, Sotirios,Markopoulos, John,Igglessi-Markopoulou, Olga
, p. 117 - 128 (2021/11/22)
A novel two step methodology for readily accessible natural “pulvinone” derivatives in excellent yields has been developed starting from activated precursors, bearing a functionalized 1,3-dioxolane-2,4-diones (OCA’s), as dually protected-activated synthon
Silver-Catalyzed tert-Butyl 3-Oxopent-4-ynoate π-Cyclizations: Controlling the Ring Size - Hydroxypyrone or Pulvinone Formation - By Counterion and Additive Optimization
Hermann, David,Brückner, Reinhard
supporting information, p. 7455 - 7460 (2019/01/03)
tert-Butyl 2,5-diaryl-3-oxopent-4-ynoates, obtained from arylacetylenes and the acid chloride of tert-butyl 2-phenylmalonate, represent strongly enolized β-ketoesters. Their C≡C bonds were activated by Ag(I) salts so that de-tert-butylating π-cyclizations
Novel synthesis of naturally occurring pulvinones: A heck coupling, transesterification, and Dieckmann condensation strategy
Bernier, David,Brueckner, Reinhard
, p. 2249 - 2272 (2008/03/12)
Phosphine-free Heck alkenylations of iodoarenes with trifluoroethyl 2-acetoxyacrylate (19) led stereoselectively to trifluoroethyl (Z)-2-acetoxycinnamates 31-34, 42, 44, and 51. Deacetylation followed by acylation with N,N′-dicyclohexylcarbodiimide activa
Synthesis and cyclization of 3-aryl-2-(arylacetoxy)acrylates: A three-step access to pulvinones
Bernier, David,Moser, Frank,Brueckner, Reinhard
, p. 2240 - 2248 (2008/03/12)
(4-Methoxybenzyl)magnesium chloride was acylated with dialkyl oxalates 14a,b,d or S,S-di-tert-butyl dithiooxalate (14c) to give 2-hydroxy-3-(4- methoxyphenyl)acrylates and -thioacrylates 17a-d. Esterification with phenylacetic anhydride or (4-methoxypheny
