952664-76-5

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-N-t-butyl-4-nitroaniline is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drug compounds.
Used in Dye and Pigment Industry:
2-Bromo-N-t-butyl-4-nitroaniline is used as a key component in the production of azo dyes and pigments, known for their wide range of colors and applications in various industries.
Used in Organic Compounds Synthesis:
2-Bromo-N-t-butyl-4-nitroaniline is used as an intermediate in the synthesis of various organic compounds, highlighting its versatility in chemical reactions and applications.

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 4138-38-9 tert-butyl(4-nitrophenyl)amine 

Downstream Products

• 952664-77-6 tert-butyl-(4-nitro-2-trimethylsilanylethynylphenyl)amine 

Relevant academic research and scientific papers

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

COMPOSITIONS FOR TREATMENT OF CYSTIC FIBROSIS AND OTHER CHRONIC DISEASES

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

Modulators of ATP-binding cassette transporters

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.