95269-17-3

Basic information

• Product Name: Benzoic acid, 4-[[3-(4-chlorophenyl)-1-oxo-2-propenyl]amino]-, ethyl ester
• CAS NO: 95269-17-3
• Molecular Formula: C18H16ClNO3
• Molecular Weight: 329.783
• Mol File: 95269-17-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[[3-(4-chlorophenyl)-1-oxo-2-propenyl]amino]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[[3-(4-chlorophenyl)-1-oxo-2-propenyl]amino]-, ethyl ester(95269-17-3)
• EPA Substance Registry System: Benzoic acid, 4-[[3-(4-chlorophenyl)-1-oxo-2-propenyl]amino]-, ethyl ester(95269-17-3)

Safety Data

• Hazardous Substances Data: 95269-17-3(Hazardous Substances Data)

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 150-13-0 4-amino-benzoic acid 
• 5338-44-3 ethyl p-acetamidobenzoate 
• 104-88-1 4-chlorobenzaldehyde 
• 35086-79-4 p-chlorocinnamoyl chloride 

Downstream Products

• 86373-82-2 4-[[3-(p-chlorophenyl)propyl]ethylamino]benzoic acid, ethyl ester 
• 86373-80-0 4-[[3-(p-chlorophenyl)propyl]methylamino]benzoic acid, ethyl ester 
• 86373-83-3 4-[[3-(p-Chlorophenyl)propyl]ethylamino]benzoic acid 
• 86373-81-1 4-[[3-(p-Chlorophenyl)propyl]methylamino]benzoic acid 
• 53901-92-1 4-[3-(4-Chloro-phenyl)-propionylamino]-benzoic acid 
• 61440-61-7 ethyl 4-[3-(p-chlorophenyl)propylamino]benzoate 
• 61440-62-8 4-<3-(p-Chlorphenyl)propylamino>benzoesaeure 
• 86373-57-1 4-(p-Chlorohydrocinnamamido)benzoic acid, ethyl ester 
• 53901-68-1 4-(p-Chlorocinnamamido)benzoic acid 

Relevant articles and documents

Microwave-mediated Green chemistry approach for the synthesis of some chalcone derivatives and evaluation of their anthelmintic activity

In the present study, microwave-mediated Green chemistry approach is followed to prepare some chalcone derivatives. For this purpose, microwave heating technology is used as the alternative energy sources to synthesize a series of chalcone derivatives by Claisen-Schmidt condensation of ethyl 4-acetamidobenzoate with various aromatic aldehydes in the presence of ethanolic sodium hydroxide solution followed by dehydration. With the help of microwave, the rate of reaction is increased with less byproduct formation and better yield of the product. The structures of the newly synthesized compounds are confirmed by FT-IR, 1H NMR, mass spectra and CHN analyses. The titled compounds are screened for their anthelmintic activity and significant activity as compared to the standard drug is found. Compounds with electron withdrawing groups are found to be highly potent among the series.