95271-93-5

Upstream product

• 69555-14-2 ethyl N-diphenylmethylene glycine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 107367-52-2 3-Oxo-3-phenyl-2-[(E)-(3-phenyl-acryloyl)amino]-propionic acid ethyl ester 
• 107367-73-7 [5-Phenyl-2-((E)-styryl)-oxazol-4-yl]-methanol 
• 107367-75-9 4-Chloromethyl-5-phenyl-2-((E)-styryl)-oxazole 
• 107367-66-8 5-Phenyl-2-((E)-styryl)-oxazole-4-carboxylic acid 
• 107614-27-7 [5-Phenyl-2-((E)-styryl)-oxazol-4-yl]-acetonitrile 
• 107367-96-4 [5-Phenyl-2-((E)-styryl)-oxazol-4-yl]-acetic acid 
• 107367-53-3 5-Phenyl-2-((E)-styryl)-oxazole-4-carboxylic acid ethyl ester 
• 1489278-43-4 ethyl 2-((S)-3-(4-(benzyloxy)phenyl)-2-(tert-butoxycarbonylamino)propanamido)-3-oxo-3-phenylpropanoate 
• 1489279-11-9 (S)-2-(2-(4-(benzyloxy)phenyl)-1-(tert-butoxycarbonylamino)ethyl)-5-phenylthiazole-4-carboxylic acid 
• 1489279-14-2 (S)-methyl 3-(2-(2-(4-(benzyloxy)phenyl)-1-(tert-butoxycarbonylamino)ethyl)-5-phenylthiazole-4-carboxamido)benzoate 
• 1489277-82-8 (S)-methyl 3-(2-(2-(4-(benzyloxy)phenyl)-1-(cyclohexanecarboxamido)ethyl)-5-phenylthiazole-4-carboxamido)benzoate 
• 1489277-85-1 (S)-methyl 3-(2-(1-(3-(1H-indol-3-yl)propanamido)-2-(4-(benzyloxy)phenyl) ethyl)-5-phenylthiazole-4-carboxamido)benzoate 
• 1489279-24-4 (S)-ethyl 2-(1-(3-(1H-Indol-3-yl)propanamido)-2-(4-(benzyloxy)phenyl)ethyl)-5-phenylthiazole-4-carboxylate 
• 1489277-88-4 (S)-3-(2-(2-(4-(benzyloxy)phenyl)-1-(cyclohexanecarboxamido)ethyl)-5-phenylthiazole-4-carboxamido)benzoic acid 

Relevant academic research and scientific papers

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The pseudotetrapeptide FR-139317 is a potent and highly selective antagonist of the endothelin-A (ET(A)) receptor; however, its peptidic nature leads to poor oral absorption characteristics which make it an unlikely drug candidate. In an attempt to improv

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.