953046-62-3 Usage
Uses
Used in Pharmaceutical Industry:
[3-(2-Fluoro-phenyl)-isoxazol-5-yl]-methanol is used as a potential pharmaceutical agent for its antimicrobial, antifungal, and anti-inflammatory properties. The isoxazole ring and the 2-fluoro-phenyl substituent may contribute to its therapeutic effects, making it a candidate for the development of new drugs targeting various infections and inflammatory conditions.
Used in Research and Development:
In the field of chemical research and development, [3-(2-Fluoro-phenyl)-isoxazol-5-yl]-methanol serves as a subject of study for its unique structural features and potential applications. [3-(2-FLUORO-PHENYL)-ISOXAZOL-5-YL]-METHANOL's properties, including the influence of the fluorine atom on the phenyl ring, are of interest for further exploration to understand its behavior and possible modifications that could enhance its pharmaceutical utility.
Used in Drug Design:
[3-(2-Fluoro-phenyl)-isoxazol-5-yl]-methanol is utilized in drug design as a structural motif that can be incorporated into new molecules to target specific biological pathways or receptors. Its unique combination of functional groups and heteroatoms may offer novel mechanisms of action or improved pharmacokinetic properties, such as increased bioavailability or selectivity for certain targets.
Check Digit Verification of cas no
The CAS Registry Mumber 953046-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,3,0,4 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 953046-62:
(8*9)+(7*5)+(6*3)+(5*0)+(4*4)+(3*6)+(2*6)+(1*2)=173
173 % 10 = 3
So 953046-62-3 is a valid CAS Registry Number.
953046-62-3Relevant academic research and scientific papers
A rapid and efficient solvent-free microwave-assisted synthesis of pyrazolone derivatives containing substituted isoxazole ring
Zhang, Dawei,Zhang, Yumin,Zhao, Tianqi,Li, Jing,Hou, Yaya,Gu, Qiang
, p. 2979 - 2987 (2016/05/19)
An efficient synthesis of 4-substituted pyrazolone derivatives was developed. 4-Substituted pyrazolone derivatives were synthesized in 78-97% yields starting from various 3-substituted isoxazole-5-carbaldehydes, ethyl acetoacetate and hydrazine under micr
ISOXAZOLE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
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Page/Page column 26, (2008/06/13)
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type or T-type calcium channel activity are disclosed. Specifically, a series of isoxazole containing compounds are disclosed of the general formula (1) where Z is N or CHNR3 and (Ar1)2CR4 is optionally substituted benzhydryl.
Synthesis and biological evaluation of novel T-type Ca2+ channel blockers
Jung, Hee Kyung,Doddareddy, Munikumar Reddy,Cha, Joo Hwan,Rhim, Hyewhon,Cho, Yong Seo,Koh, Hun Yeong,Jung, Bong Young,Pae, Ae Nim
, p. 3965 - 3970 (2007/10/03)
A small molecule library of piperazinylalkylisoxazole derivatives containing about 600 compounds was designed, synthesized and evaluated for blocking effects on T-type Ca2+ channel. Several ligands were identified to possess high inhibitory activity against the T-type Ca 2+ channel. The compound 21 with trifluoromethyl substituents at C3-position of phenyl group (R1) and C2- position of phenyl group (R2) showed the highest inhibitory activity with IC50 value of 1.02μM, which is comparable to that of mibefradil.
