953084-91-8Relevant academic research and scientific papers
Rh-Catalyzed Anti-Markovnikov Hydrocyanation of Terminal Alkynes
Ye, Fei,Chen, Junting,Ritter, Tobias
, p. 7184 - 7187 (2017)
We report the first highly stereo- and regioselective hydrocyanation of terminal alkynes to furnish E-configured alkenyl nitriles. Acrylonitriles can be accessed on gram scale with broad substrate scope and functional group tolerance. The hydrocyanation reaction employs acetone cyanohydrin as a practical alternative to HCN gas.
PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES
-
Page/Page column 19; 20, (2018/12/13)
The present invention refers to a process for a Rh-catalyzed Anti-Markovnikov hydrocyanation of terminal alkynes which process discloses, for the first time, the highly stereo- and regio-selective hydrocyanation of terminal alkynes to furnish E- configured alkenyl nitriles and the catalyst used in the present process.
ANTIBACTERIAL AGENTS
-
Page/Page column 249, (2009/01/24)
Antibacterial compounds of formula (I) are provided, as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.
