95337-69-2 Usage
Uses
Used in Pharmaceutical Research:
1-[1-(4-BROMOPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2,2,2-TRIFLUORO-1-ETHANONE is used as a building block for drug development due to the biological activity of pyrroles, which are known to have potential therapeutic applications.
Used in Chemical Synthesis:
In the field of synthetic chemistry, 1-[1-(4-BROMOPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2,2,2-TRIFLUORO-1-ETHANONE is used as a reactive intermediate for the synthesis of various complex organic compounds, leveraging its bromophenyl group and trifluoroethanone moiety to participate in a range of chemical reactions.
Used in Drug Discovery:
1-[1-(4-BROMOPHENYL)-2,5-DIMETHYL-1H-PYRROL-3-YL]-2,2,2-TRIFLUORO-1-ETHANONE is utilized in drug discovery processes to explore its potential as a precursor or component in the creation of new pharmaceutical agents, given its unique structural features and the known biological relevance of pyrrole-containing compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 95337-69-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,3,3 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 95337-69:
(7*9)+(6*5)+(5*3)+(4*3)+(3*7)+(2*6)+(1*9)=162
162 % 10 = 2
So 95337-69-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H11BrF3NO/c1-8-7-12(13(20)14(16,17)18)9(2)19(8)11-5-3-10(15)4-6-11/h3-7H,1-2H3
95337-69-2Relevant academic research and scientific papers
Protection of Primary Amines as N-Substituted 2,5-Dimethylpyrroles
Bruekelman, Stephen P.,Leach, (Miss) Susan E.,Meakins, G. Denis,Tirel, Malcolm D.
, p. 2801 - 2807 (2007/10/02)
Protection of primary amine group is achieved by incorporating it into an N-substituted 2,5-dimethylpyrrole system.The method affords protection against strong bases and nucleophiles, heating with concentrated alkali, standard mineral acid work-up conditions, and various other reagents.Phenyl-, pyridil-, thiazolyl-, and alkyl-amines have been studied.All give trisubstituted pyrroles in high yield (>80percent) by reaction with hexane-2,5-dione.The pyrroles from the first three types are stable to storage; even the N-alkyl compounds can be used without difficulty.Regeneration of the amine group, by treatment with hydrxylamine hydrochloride, is efficient (80percent yield) with the phenyl, pyridyl, and alkyl compounds but less satisfactory (60 - 65percent generally but down to 25percent in two cases) with the thiazolyl derivatives.
