953395-17-0Relevant academic research and scientific papers
Synthesis of Fused Indoline-Cyclobutanone Derivatives via an Intramolecular [2+2] Cycloaddition
Neyyappadath, Rifahath M.,Greenhalgh, Mark D.,Cordes, David B.,Slawin, Alexandra M. Z.,Smith, Andrew D.
, p. 5169 - 5174 (2019)
A serendipitously-discovered process for the synthesis of heterocyclic products containing a novel fused indoline-cyclobutanone ring system is reported. This process is believed to take place through in situ generation of a ketene intermediate, followed b
Biomimetic aerobic oxidation of amino alcohols to lactams
Babu, Beneesh P.,Endo, Yoshinori,Baeckvall, Jan-E.
supporting information, p. 11524 - 11527,4 (2012/12/11)
The right path: N-Protected amino alcohols undergo aerobic and biomimetic oxidation to the corresponding lactams in the presence of a ruthenium catalyst and a combination of electron-transfer mediators under air (see scheme). The reaction was used for the synthesis of five-, six-, and seven-, membered lactams and showed good tolerance to a number of N-protecting groups. Copyright
