953802-78-3

Upstream product

• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 846023-33-4 4-bromo-3-ethoxyaniline hydrochloride 

Downstream Products

• 953804-27-8 ethyl 4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-morpholin-4-ylquinoline-3-carboxylate 
• 953801-12-2 ethyl 4-((2,4-difluorophenyl)amino)-7-ethoxy-6-(4-methylpiperazin-1-yl)quinoline-3-carboxylate 
• 953801-39-3 ethyl 4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-(4-hydroxypiperidin-1-yl)quinoline-3-carboxylate 
• 953801-30-4 ethyl 4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-(4-ethylpiperazin-1-yl)quinoline-3-carboxylate 
• 953801-45-1 ethyl 4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-(4-methyl-1,4-diazepan-1-yl)quinoline-3-carboxylate 
• 953801-41-7 ethyl 4-[(2,4-difluorophenyl)amino]-7-ethoxy-6-(4-isopropylpiperazin-1-yl)quinoline-3-carboxylate 
• 953802-23-8 ethyl 6-[4-(tert-butoxycarbonyl)-1,4-diazepan-1-yl]-4-[(2,4-difluorophenyl)amino]-7-ethoxyquinoline-3-carboxylate 
• 953802-22-7 ethyl 6-(4-(tert-butoxycarbonyl)piperazin-1-yl)-4-((2,4-difluorophenyl)amino)-7-ethoxyquinoline -3-carboxylate 

Relevant academic research and scientific papers

Synthesis and initial in vivo evaluation of [11C]AZ683-A Novel PET Radiotracer for Colony Stimulating Factor 1 Receptor (CSF1R)

Positron emission tomography (PET) imaging of Colony Stimulating Factor 1 Receptor (CSF1R) is a new strategy for quantifying both neuroinflammation and inflammation in the periphery since CSF1R is expressed on microglia and macrophages. AZ683 has high aff

CHEMICAL COMPOUNDS

The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the huma

4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS

The invention relates to chemical compounds of formula IA or IB: formula IA IB or pharmaceutically acceptable salts thereof which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of tr