953805-23-7

Basic information

• Product Name: 3-{(2R,3S)-3-[(4-fluorophenyl)amino]-2-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-3-[4-(trimethylsilanyloxy)phenyl]propanoyl}-(4S)-4-phenyl-1,3-oxazolidin-2-one.
• Synonyms: 3-{(2R,3S)-3-[(4-fluorophenyl)amino]-2-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-3-[4-(trimethylsilanyloxy)phenyl]propanoyl}-(4S)-4-phenyl-1,3-oxazolidin-2-one.
• CAS NO: 953805-23-7
• Molecular Weight: 728.908
• Mol File: 953805-23-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{(2R,3S)-3-[(4-fluorophenyl)amino]-2-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-3-[4-(trimethylsilanyloxy)phenyl]propanoyl}-(4S)-4-phenyl-1,3-oxazolidin-2-one.(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{(2R,3S)-3-[(4-fluorophenyl)amino]-2-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-3-[4-(trimethylsilanyloxy)phenyl]propanoyl}-(4S)-4-phenyl-1,3-oxazolidin-2-one.(953805-23-7)
• EPA Substance Registry System: 3-{(2R,3S)-3-[(4-fluorophenyl)amino]-2-[2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-3-[4-(trimethylsilanyloxy)phenyl]propanoyl}-(4S)-4-phenyl-1,3-oxazolidin-2-one.(953805-23-7)

Safety Data

• Hazardous Substances Data: 953805-23-7(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 953805-20-4 3-{4-[2-(4-fluorophenyl)-5,5-dimethyl-[1,3]dioxin-2-yl]butyryl}(4S)-phenyl-1,3-oxazolidin-2-one 
• 3382-63-6 (E)-(4-hydroxy-benzylidene)-(4-fluorophenyl)-amine 

Downstream Products

• 953805-25-9 4(S)-(4-trimethylsilanyloxyl)-1-(4-fluorophenyl)-3(R)-{2-[2-(4-fluorophenyl)-5,5-dimethyl-[1,3]-dioxan-2-yl]-ethyl}azetidine-2-one 

Relevant articles and documents

PROCESSES FOR THE SYNTHESIS OF AZETIDINONE

Provided are intermediates useful for the synthesis of hydroxyl-alkyl substituted azetidinones, processes of their preparation, and processes for the synthesis of certain hydroxyl-alkyl substituted azetidinones. Also provided are processes for the synthesis ofl-(4-fluorophenyl)-3(R)-[3-(4-fluorophenyl)-3(S)- hydroxypropyl]-4(S)-(4-hydroxyphenyl)-2-azetidinone, or ezetimibe.