95398-76-8Relevant academic research and scientific papers
Suzuki-Miyaura monocouplings of p-dibromobiphenyl and substituted p-dibromo(penta-p-phenylenes)
Guillén, Elena,Hierrezuelo, Jesús,Martínez-Mallorquín, Rocio,López-Romero, J. Manuel,Rico, Rodrigo
experimental part, p. 2555 - 2561 (2011/04/26)
The mono/bis ratio for the Suzuki-Miyaura cross coupling of p-dibromobiphenyl and p-dibromo(pentap-phenylenes) with arylboronic acids and esters has been studied. The coupling reaction is demonstrated to be highly selective for monoarylation when the substrate is a p-dibromooligoarene, while selective biarylation is obtained for p-diiodoterphenyl. The mono/bis coupling-ratio for these compounds was highly sensitive to the nature of the halogen involved, however steric hindrance or electronic characteristics of the boronic derivative did not affect the selectivity of the reaction. The reaction yields observed were higher at room temperature and when arylboronic pinacol esters were used. These reactions also offer a useful method for the preparation of asymmetrically substituted terphenyls and hexa-p-phenylenes, giving good yields.
