95412-20-7Relevant articles and documents
The application of (Z)-3-aryl-3-haloenoic acids to the synthesis of (Z)-5-benzylidene-4-arylpyrrol-2(5H)-ones
Gupton, John T.,Telang, Nakul,Banner, Edith J.,Kluball, Emily J.,Hall, Kayleigh E.,Finzel, Kara L.,Jia, Xin,Bates, Spencer R.,Welden, R. Scott,Giglio, Benjamin C.,Eaton, James E.,Barelli, Peter J.,Firich, Lauren T.,Stafford, John A.,Coppock, Matthew B.,Worrall, Eric F.,Kanters, Rene P.F.,Keertikar, Kerry,Osterman, Rebecca
experimental part, p. 9113 - 9122 (2011/01/12)
Studies directed at the synthesis of (Z)-5-benzylidene-4-arylpyrrol-2(5H)- ones from (Z)-3-aryl-3-haloenoic acids are described. The successful strategy relies on the preparation of (Z)-3-aryl-3-haloenoic acids from acetophenones through the corresponding
INVESTIGATIONS IN THE SERIES OF SUBSTITUTED BUTAN- AND BUTENOLIDES. III. SYNTHESIS OF ARYLBUTAN- AND ARYLBUTENOLIDES AND THEIR PROPERTIES
Chellar, N. S.,Badovskaya, L. A.,Ignatenko, A. V.
, p. 1775 - 1779 (2007/10/02)
A new method was developed for the synthesis of 2-aryl- and 3-aryl-2-buten-4-olides by the arylation of 2-buten-4-olide with diazonium halides in the presence of cupric chloride as catalyst.The intermediate products of the reaction are the corresponding arylchlorobutanolides. 4-R-Methylene-3-aryl-2-buten-4-olides and 4-hydroxy-3-aryl-2-butenamides were obtained in the reaction of 3-aryl-2-buten-4-olides with aldehydes and primary aliphatic amines respectively.Some of the synthesized compounds have antimicrobial and growth-stimulant activity.
