954145-07-4Relevant academic research and scientific papers
Total synthesis of (-)-platensimycin, a novel antibacterial agent
Ghosh, Arun K.,Xi, Kai
body text, p. 1163 - 1170 (2009/08/15)
An enantioselective synthesis of platensimycin, a novel antibiotic natural product that inhibits bacterial β-ketoacyl-(acyl-carrier-protein) synthase (FabF), is described. Our synthetic strategy for the construction of the oxatetracyclic core involved an
Enantioselective synthesis of (-)-platensimycin oxatetracyclic core by using an intramolecular Diels-Alder reaction
Ghosh, Arun K.,Kai, Xi
, p. 4013 - 4016 (2008/02/12)
An enantioselective route to the oxatetracyclic core of (-)-platensimycin (1) has been investigated by using an intramolecular Diels-Alder reaction as the key step. The thermal reaction of E/Z mixture (1:1) provided oxatetracyclic core 2 from the E-diene
