95448-04-7Relevant academic research and scientific papers
Electrophilic trifluoromethylthiolation of carbonyl compounds
Alazet, Sebastien,Zimmer, Luc,Billard, Thierry
, p. 8589 - 8593 (2014)
A general method for the α-trifluoromethylthiolation of carbonyl compounds, without prefunctionalization, has been developed. Aldehydes, ketones, esters, amides, keto-esters, alkaloids, and steroids have been trifluoromethylthiolated with good yields. This work, proposing a new reagent for electrophilic trifluoromethylthiolation, provides a route towards the original synthesis of various trifluoromethylthiolated molecules for further applications.
