954901-22-5Relevant academic research and scientific papers
Reactions of 2-carbonyl- And 2-hydroxy(or methoxy)alkylsubstituted benzimidazoles with arenes in the superacid CF3SO3H. NMR and DFT studies of dicationic electrophilic species
Ryabukhin, Dmitry S.,Turdakov, Alexey N.,Soldatova, Natalia S.,Kompanets, Mikhail O.,Ivanov, Alexander Yu.,Boyarskaya, Irina A.,Vasilyev, Aleksander V.
supporting information, p. 1962 - 1973 (2019/09/03)
Reactions of 2-carbonyl- and 2-hydroxy(or methoxy)alkylbenzimidazoles with arenes in the Br?nsted superacid TfOH resulted in the formation of the corresponding Friedel-Crafts reaction products, 2-diarylmethyl and 2-arylmethyl-substituted benzimidazoles, in yields up to 90%. The reaction intermediates, protonated species derived from starting benzimidazoles in TfOH, were thoroughly studied by means of NMR and DFT calculations and plausible reaction mechanisms are discussed.
Pd(0)-catalyzed diarylation of sp3 C-H bond in (2-azaaryl)methanes
Song, Guoyong,Su, Yan,Gong, Xue,Han, Keli,Li, Xingwei
supporting information; experimental part, p. 1968 - 1971 (2011/06/25)
A highly efficient and selective palladium-catalyzed diarylation of (2-azaaryl)methanes at the methyl group is described. Aryl chlorides proved reactive enough. A palladium η3-azaallyl intermediate has been identified on the basis of DFT studies.
