95495-03-7Relevant academic research and scientific papers
5-Bromo-2-iodopyrimidine: A novel, useful intermediate in selective palladium-catalysed cross-coupling reactions for efficient convergent syntheses
Goodby, John W.,Hird, Michael,Lewis, Robert A.,Toyne, Kenneth J.
, p. 2719 - 2720 (2007/10/03)
A simple synthesis of the novel 5-bromo-2-iodopyrimidine is described and examples are provided of the use of the compound in selective palladium-catalysed cross-coupling reactions with a wide range of arylboronic acids and alkynylzincs to give the efficient syntheses of many substituted pyrimidine compounds.
Fluorine-containing pyrimidine derivatives
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, (2008/06/13)
Liquid crystalline fluorine-containing pyrimidine compounds have the formula I STR1 wherein R1 and R2 are H, R, OR or OCOR, and one of them can also be CN or F, or, if A is a covalent bond, also one or both of R1 and R2 can be 4-R4 -phenyl or 4-R-cyclohexyl, wherein R4 is R, OR, cyano, f or OCOR; wherein R is an alkyl group of 1 to 12 C atoms; R3 is F or, if one of the radicals R1 or R2 is F or 4-fluorophenyl, also H; Z is 1,3-pyrimidin-2,5-diyl; and A is 1,4-phenylene, 1,4-cyclohexylene or a covalent bond. Fluorine-containing pyrimidine compounds are useful components of liquid crystal dielectrics for electro-optical display devices.
