955029-65-9Relevant academic research and scientific papers
Synthesis and biological effects of small molecule enhancers for improved recombinant protein production in plant cell cultures
Rebelo, Bárbara A.,Santos, Rita B.,Ascenso, Osvaldo S.,Nogueira, Ana Cláudia,Lousa, Diana,Abranches, Rita,Ventura, M. Rita
, (2019/12/24)
Histone deacetylases are involved in chromatin remodelling and thus play a vital role in the epigenetic regulation of gene expression. HDAC inhibitors alter the acetylation status of histone and non-histone proteins to regulate various cellular events suc
DETECTION OF HISTONE DEACETYLASE INHIBITION
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Page/Page column 16; 9/10, (2008/06/13)
Provided are compositions and methods for intracellular detection of enzyme activity. One example of a composition is a histone deacetylase substrate comprising a compound of the following formula (I): One example of a method is a method for detecting histone deacetylase activity comprising introducing a compound according to formula (1) to a plurality of cells and monitoring the cells with magnetic resonance spectroscopy.
