955095-32-6Relevant academic research and scientific papers
Soluble-support-assisted electrochemical reactions: Application to anodic disulfide bond formation
Kitada, Shingo,Takahashi, Masahito,Yamaguchi, Yusuke,Okada, Yohei,Chiba, Kazuhiro
, p. 5960 - 5963 (2013/02/26)
A soluble-support-assisted technique was successfully applied to electrochemical reactions, leading to anodic disulfide bond formation. The support-bound peptide was soluble in electrolyte solution, allowing electron transfer at the surface of the electrodes. After completion of the reaction, the support-bound product was recovered as a precipitate by simple dilution of the reaction mixture with poor solvent.
PRODUCTION METHOD OF OLIGONUCLEOTIDE
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, (2012/12/13)
The problem of the present invention is provision of a method of producing an n+p-mer oligonucleotide efficiently in a high yield, which includes use of, as a starting material, an n-mer oligonucleotide wherein the 3′-terminal hydroxyl group is protected,
Hydrophobic tag-assisted liquid-phase synthesis of a growth hormone-inhibiting peptide somatostatin
Kitada, Shingo,Fujita, Shuji,Okada, Yohei,Kim, Shokaku,Chiba, Kazuhiro
scheme or table, p. 4476 - 4479 (2011/09/15)
Hydrophobic tag-assisted liquid-phase peptide synthesis technique and disulfide bond formation have been well-combined, leading to the efficient and practical preparation of a growth hormone-inhibiting peptide somatostatin. Intramolecular disulfide bond f
REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT
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Page/Page column 18, (2009/01/24)
A reagent for organic synthesis with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic synthesis reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process development. With the reagent, research on and development of, e.g., medicines through, e.g., compound library synthesis, etc. can be accelerated. It can hence contribute to technical innovations in the biochemical industry and chemical industry.
