95517-07-0

Basic information

• Product Name: 1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE
• Synonyms: 6-ACETYL-5-HYDROXYTETRALIN;1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE;1-(5,6,7,8-Tetrahydro-1-hydroxy-naphthalen-2-yl)ethanone;2-Acetyl-5,6,7,8-tetrahydro-1-naphthol;Ethanone, 1-(5,6,7,8-tetrahydro-1-hydroxy-2-naphthalenyl)-;6-acetyl-5-hydroxytetraline;6-ACETYL-5-HYDROXYTETRALIN(WXG01621)
• CAS NO: 95517-07-0
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.24
• Mol File: 95517-07-0.mol

Chemical Properties

• Melting Point: 46.5-47 °C(Solv: ethanol (64-17-5))
• Boiling Point: 348.9 °C at 760 mmHg
• Flash Point: 148.6 °C
• Appearance: /
• Density: 1.156 g/cm³
• PKA: 10.78±0.20(Predicted)
• Water Solubility: at 25 deg C (mg/L): 1.285e+004
• CAS DataBase Reference: 1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE(95517-07-0)
• EPA Substance Registry System: 1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE(95517-07-0)

Safety Data

• Hazardous Substances Data: 95517-07-0(Hazardous Substances Data)

Usage

Uses

Used in Fragrance and Flavor Industry:
1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE is used as a key ingredient in the production of fragrances and flavors due to its aromatic properties, enhancing the sensory experience of various consumer products.
Used in Pharmaceutical Industry:
1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE is used as an intermediate in the synthesis of pharmaceutical compounds, leveraging its hydroxy and ketone functional groups for versatile chemical reactions to create new medicinal agents.
Used in Agrochemical Industry:
1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE is used as a precursor in the development of agrochemicals, contributing to the creation of new compounds for agricultural applications, such as pesticides and herbicides.
Used in Organic Synthesis:
1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE is used as a versatile intermediate in organic synthesis, enabling the formation of a wide range of organic compounds for various applications across different industries.
Safety Considerations:
It is important to handle 1-(1-HYDROXY-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ETHANONE with care due to its potential health hazards and flammability, ensuring proper safety measures are in place during its use and storage.

Upstream product

• 529-35-1 5,6,7,8-Tetrahydronaphthalen-1-ol 
• 75-36-5 acetyl chloride 
• 570-08-1 diethyl acetylmalonate 
• 78-27-3 1-Ethynylcyclohexan-1-ol 
• 91028-13-6 5,6,7,8-tetrahydronaphthalen-1-yl acetate 

Downstream Products

• 1523493-78-8 2-chloro-4-hydroxy-3-(5-hydroxytetralin-6-yl)-5-phenyl-7H-thieno[2,3-b]pyridin-6-one potassium salt 
• 857236-46-5 1-(1-hydroxy-5,6,7,8-tetrahydro-[2]naphthyl)-3-phenyl-propane-1,3-dione 
• 913721-70-7 1-benzyloxy-2-acetyl-5,6,7,8-tetrahydronaphthalene 

Relevant articles and documents

MODULATORS OF STIMULATOR OF INTERFERON GENES (STING)

The present invention relates to compounds of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof that are useful as modulators of STING (Stimulator of Interferon Genes). The present invention further relates to the compounds of formula (I) for use as a medicament and to a pharmaceutical composition comprising said compounds.

WB4101-related compounds: New, subtype-selective α1- adrenoreceptor antagonists (or inverse agonists?)

Our previous structure-affinity relationship study had considered the enantiomers of the naphthodioxane, tetrahydronaphthodioxane, and 2-methoxy-1-naphthoxy analogues (compounds 1, 3, and 2, respectively) of 2-(2,6-dimethoxyphenoxyethylaminomethyl)-1,4-be

Titanium(IV) chloride-mediated ortho-acylation of phenols and naphthols

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