95535-40-3

Usage

Uses

Used in Organic Synthesis:
4-Vinylsulfonylbenzoic acid is used as an intermediate in organic synthesis for the preparation of a wide range of chemical compounds. Its reactive vinyl and sulfonyl groups allow for various chemical reactions, such as addition, substitution, and condensation, enabling the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Vinylsulfonylbenzoic acid is used as a building block for the development of new drugs. Its unique structure can be incorporated into drug molecules to impart specific biological activities, such as anti-inflammatory, analgesic, or antimicrobial properties.
Used in Chemical Research:
4-Vinylsulfonylbenzoic acid is also utilized in chemical research as a model compound to study various reaction mechanisms and to develop new synthetic methodologies. Its reactivity and functional groups make it an ideal candidate for exploring novel chemical transformations and understanding reaction pathways.
Used in Material Science:
In the field of material science, 4-Vinylsulfonylbenzoic acid can be used as a monomer or a comonomer in the synthesis of polymers with specific properties. Its vinyl group can undergo polymerization reactions, leading to the formation of polymers with tailored characteristics, such as improved mechanical strength, thermal stability, or chemical resistance.
Overall, 4-Vinylsulfonylbenzoic acid is a versatile carboxylic acid derivative with a wide range of applications in various industries, including organic synthesis, pharmaceuticals, chemical research, and material science. Its unique molecular structure and reactivity make it a valuable compound for the development of new chemical entities and materials.

InChI:InChI=1/C9H8O4S/c1-2-14(12,13)8-5-3-7(4-6-8)9(10)11/h2-6H,1H2,(H,10,11)

Upstream product

• 1074-36-8 4-mercaptobenzoic acid 
• 7184-99-8 4-((2-hydroxyethyl)thio)benzoic acid 
• 7180-09-8 2-(4-carboxyphenylsulphonyl)ethanol 
• 150-13-0 4-amino-benzoic acid 
• 1155-51-7 4,4'-Dithiobisbenzoic acid 
• 7185-00-4 4-<(2-Chlorethyl)sulfonyl>benzoylchlorid 
• 17918-95-5 4-(2-Chloroethylsulfonyl)-benzoic acid 

Downstream Products

• 343934-41-8 2,5-dioxopyrrolidin-1-yl 4-(vinylsulfonyl)benzoate 

Relevant academic research and scientific papers

Solid phase synthesis of bicyclic pyrrolidines

The preparation of bicyclic pyrrolidines, stable and easy to isolate, is performed through both classical solution chemistry and on solid support. A new linker strategy is presented based on the concept of REM resin approach. Starting from a suitably derivatized Wang's resin, the linker can be REgenerated after cleavage of the product and functionalized to start a new synthetic cycle via a Michael reaction. In the present work a vinyl sulfone supported on a Wang's resin is able to undergo a Michael reaction with an amino acid derivative; the obtained adduct serves as a precursor for azomethine ylide generation, which is conveniently trapped with N-methyl-maleimide. The results are presented and discussed in the light of the experimental conditions applied as well as the method chosen for the cleavage of the product and resin regeneration.

Site-Selective Functionalization of Methionine Residues via Photoredox Catalysis

Bioconjugation technologies have revolutionized the practice of biology and medicine by allowing access to novel biomolecular scaffolds. New methods for residue-selective bioconjugation are highly sought to expand the toolbox for a variety of bioconjugati

Fluorescent and Nonfluorescent Aryl Vinyl Sulfones - Reagents Suitable for Protection and Detection of Thiol Functions

The rate of the addition of primary, secondary, and tertiary thiols to aryl/alkyl vinyl sulfones 1 and 4-7 is investigated by competing reactions and by kinetics.The obtained acid stable 2-(alkyl-/arylthio)ethyl sulfones are cleaved by bases to give the starting material by rates corresponding to the rates of addition.Therefore, selective introduction and selective elimination of different (arylsulfonyl)ethyl protective groups in the same molecule is possible by using different kinetic steering factors. - Application of the fluorescent vinyl sulfones 5, 10, and 11 opens new fields for analysis and synthesis.SH-selective vinyl sulfones and thiophosphinic acid cyanides are "orthogonal" protective groups.