955376-52-0Relevant academic research and scientific papers
Synthesis and evaluation of N-methyl and S-methyl 11C-labeled 6-methylthio-2-(4′-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as radioligands for imaging β-amyloid plaques in Alzheimer's disease
Cai, Lisheng,Liow, Jeih-San,Zoghbi, Sami S.,Cuevas, Jessica,Baetas, Cesar,Hong, Jinsoo,Shetty, H. Umesha,Seneca, Nicholas M.,Brown, Amira K.,Gladding, Robert,Temme, Sebastian S.,Herman, Mary M.,Innis, Robert B.,Pike, Victor W.
, p. 148 - 158 (2008/09/19)
6-Thiolato-substituted 2-(4′-N,N-dimethylamino)phenylimidazo[ 1,2-a]pyridines (RS-IMPYs; 1-4) were synthesized as candidates for labeling with carbon-11 (t1/2 = 20.4 min) and imaging of Aβ plaques in living human brain using positron
