474012-75-4Relevant articles and documents
Radiosynthesis of SPECT tracers: Via a copper mediated 123I iodination of (hetero)aryl boron reagents
Wilson, Thomas C.,McSweeney, Greg,Preshlock, Sean,Verhoog, Stefan,Tredwell, Matthew,Cailly, Thomas,Gouverneur, Véronique
, p. 13277 - 13280 (2016/11/17)
A general method for the copper mediated nucleophilic 123I-iodination of (hetero)aryl boronic esters and acids has been developed. The broad substrate scope of this radiosynthetic approach allows access to [123I]DPA-713, [123I]IMPY, [123I]MIBG and [123I]IPEB that are four commonly used SPECT radiotracers. Our results infer that aryl boronic reagents can now be employed as common precursors for both fluorine-18 and iodine-123 radiolabelling.
Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging β-amyloid in Alzheimer's disease
Zeng, Fanxing,Southerland, Jeanine A.,Voll, Ronald J.,Votaw, John R.,Williams, Larry,Ciliax, Brian J.,Levey, Allan I.,Goodman, Mark M.
, p. 3015 - 3018 (2007/10/03)
Two new fluorinated imidazo[1,2-a]pyridine derivatives, 6-(2′-fluoroethyl)-2-(4′-dimethylamino)phenylimidazo[1,2-a]pyridine (FEPIP) and 6-(3′-fluoropropyl)-2-(4′-dimethylamino)phenylimidazo[1,2-a]pyridine (FPPIP), were synthesized. The binding affinity fo
Novel probes for imaging amyloid: iodinated benzothiazole derivatives
Zhuang, Z. P.,Kung, M.-P.,Hou, C.,Lee, C.-W.,Trojanowski, J. Q.,Lee, V. M.-Y.,Kung, H. F.
, p. S29 - S32 (2007/10/03)
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