95597-96-9Relevant academic research and scientific papers
Penam derivatives and salts thereof, and antibacterial agent comprising the same
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, (2008/06/13)
A penam derivative represented by the following general formula or a salt thereof: STR1 wherein R1 represents a hydrogen atom, an amino-protecting group or an acyl group; R2 represents a hydrogen atom or a lower alkyl group; R3
Cephem compounds
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, (2008/06/13)
β-Lactam antibiotics are disclosed which have the formulae (Ia) or pharmaceutically acceptable salts or pharmaceutically acceptable in vivo hydrolysable esters thereof: STR1 wherein R1 is phenyl, substituted phenyl, cyclohexenyl, cyclohexadieny
Beta-lactam antibacterial agents
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, (2008/06/13)
A compound having the partial structure (A): STR1 wherein n is 1 or 2.
7-Substituted aminoacetamido oxadethiacephalosporins
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, (2008/06/13)
Antibacterial 7-substituted aminoacetamido oxadethiacephalosporins of the formula: STR1 [wherein R is substituted amino, substituted phenyl, or 5- or 6-membered hetero ring; Ar is aryl; Y is hydrogen or methoxy; Het is 5- or 6-membered aromatic hetero ring; and Z is hydroxy or carboxy protecting group] preparable e.g. by acylation of 7α-methoxy-7β-amino-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives, are highly active against gram-positive and gram-negative bacteria, especially those resistant to other cephalosporins and penicillins.
