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956-90-1 Usage


Phencyclidine hydrochloride (PCP) is a psychoactive drug that has inhibitory, excitatory, analgesic and hallucinogenic effects on the central nervous system. Its chemical name is 1-(1-phenylcyclohexane)piperidine. It is a dissociative drug once used by anesthesiologists as an anesthetic with hallucinogenic and neurotoxic effects.

Chemical Properties

Crystalline Solid


Controlled substance (depressant). Anesthetic (intravenous).

Biological Activity

Non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats.

Biochem/physiol Actions

σ opioid receptor agonist and psychostimulant; inhibits NMDA glutamate receptor activation by binding to an allosteric site within the ion channel.

Safety Profile

Poison by ingestion,subcutaneous, intravenous, and intraperitoneal routes.Human systemic effects by ingestion and intravenousroutes: distorted perceptions, euphoria, excitement,hallucinations, and paresthesia. An experimental teratogen.Other experime

Check Digit Verification of cas no

The CAS Registry Mumber 956-90-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,5 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 956-90:
101 % 10 = 1
So 956-90-1 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017


1.1 GHS Product identifier

Product name 1-(1-phenylcyclohexyl)piperidine,hydrochloride

1.2 Other means of identification

Product number -
Other names Sernyl hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:956-90-1 SDS

956-90-1Relevant articles and documents

New morpholine analogues of phencyclidine: Chemical synthesis and pain perception in rats

Ahmadi, Abbas,Khalili, Mohsen,Hajikhani, Ramin,Naserbakht, Moslem

, p. 227 - 233 (2013/01/09)

Phencyclidine (PCP, I) and most its derivatives have demonstrated some pharmacological effects. Accordingly, in this study, the new methoxy (III) and hydroxy-methyl (IV) morpholine PCP derivatives were synthesized. The acute and chronic pain activities of these drugs (III, IV) were investigated by tail immersion and formalin tests on rats and the results were compared with those in PCP, PCM (PCP-morpholine, II), and methyl-PCM (V). Findings indicated that III (6 mg/kg, i.p.) generates more analgesic effects in tail immersion test in comparison with I and II in 20, 40, 45 and 55 min post-injection. These effects were observed in 10, 20, 40, 45 and 50 min after the application of IV (at the same dosage). This analgesic effect was markedly seen in 20, 40, 45 and 50 min after compound IVs application in comparison with the drugs (I-V). In formalin test analysis, the acute chemical pain (Phase I) could not be affected by any drugs (I-V) while chronic formalin pain would be diminished by these new synthesized drugs (III and IV), especially in late Phase II, compared to I and II at the dosage of 6 mg/kg. It is, therefore, concluded that these new synthesized PCP derivates including methoxy-PCM (III) and hydroxy-methyl-PCM (IV) could substantially and respectively diminish acute thermal and chronic chemical pains.