956101-10-3 Usage
General Description
2-Chloro-7-fluoroquinazoline is a synthetic chemical compound that belongs to the class of quinazoline derivatives. It is characterized by the presence of a chlorine atom at the 2-position and a fluorine atom at the 7-position of the quinazoline ring. 2-Chloro-7-fluoroquinazoline has potential applications in pharmaceutical research, particularly in the development of novel drugs targeting various biological processes. Its unique structure and chemical properties make it a valuable building block for the synthesis of diverse bioactive molecules. Additionally, 2-Chloro-7-fluoroquinazoline may also find applications in the field of agrochemicals and material science due to its versatile reactivity and potential for creating new functional materials. Overall, the synthesis and study of this chemical hold promise for the advancement of chemistry and the discovery of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 956101-10-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,6,1,0 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 956101-10:
(8*9)+(7*5)+(6*6)+(5*1)+(4*0)+(3*1)+(2*1)+(1*0)=153
153 % 10 = 3
So 956101-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H4ClFN2/c9-8-11-4-5-1-2-6(10)3-7(5)12-8/h1-4H
956101-10-3Relevant articles and documents
Eco-efficient one-pot synthesis of quinazoline-2,4(1H,3H)-diones at room temperature in water
Tian, Xin-Chuan,Huang, Xing,Wang, Dan,Gao, Feng
, p. 824 - 829 (2016/10/06)
An efficient one-pot synthesis of quinazoline-2,4(1H,3H)-diones was developed. First, the reactions of anthranilic acid derivatives with potassium cyanate afforded the corresponding urea derivatives. Then, cyclization of the urea derivatives with NaOH afforded the monosodium salts of benzoylene urea. Finally, HCl treatment afforded the desired products in near-quantitative yields. This is an eco-efficient method because all the reactions were carried out in water, and the desired products were obtained simply by filtration. The aqueous filtrate was the only waste generated from the reaction. We scaled up the reaction to 1 kg starting material, thus establishing an alternative approach for the green synthesis of quinazoline-2,4(1H,3H)-diones in the chemical and pharmaceutical industries.
