956104-76-0Relevant academic research and scientific papers
Synthetic method of dolutegravir key intermediate (R)-3-aminobutanol
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Paragraph 0018; 0019; 0020, (2017/08/29)
The invention discloses a synthetic method of dolutegravir key intermediate (R)-3-aminobutanol. The synthesis route is disclosed in the invention, and is suitable for industrialized large-scale production of (R)-3-aminobutanol; product optical purity is increased effectively; using of raw materials dangerous in operation is avoided; product yield is extremely high; and the synthetic method is suitable for industrialized popularization and application.
