956267-47-3Relevant academic research and scientific papers
[123I]-celecoxib analogues as SPECT tracers of cyclooxygenase-2 in inflammation
Uddin, Md. Jashim,Crews, Brenda C.,Ghebreselasie, Kebreab,Tantawy, Mohammed N.,Marnett, Lawrence J.
, p. 160 - 164 (2011)
We report the synthesis and evaluation of a series of iodinated celecoxib analogues as cyclooxygenase-2 (COX-2)-targeted single photon emission computerized tomography (SPECT) imaging agents for the detection of inflammation. The structure-activity relati
Substituted piperazines as metabotropic glutamate receptor antagonists
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Page/Page column 17, (2008/06/13)
The invention relates to compounds of formula I or pharmaceutically acceptable salts or solvates thereof: where Ar1, Ar2, Hy, L, R1, m and n are as defined in the description. The invention also includes pharmaceutical compositions and uses thereof, processes for making the compounds, as well as methods for the medical treatment of mGluR5-mediated disorders.
MGluR5 modulators VI
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Page/Page column 10-11, (2008/06/13)
The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.
MGluR5 modulators V
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Page/Page column 16, (2008/06/13)
The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.
