95630-75-4

Usage

InChI:InChI=1/C10H17NO2.ClH/c1-2-13-10(12)8-6-3-4-7(5-6)9(8)11;/h6-9H,2-5,11H2,1H3;1H/t6-,7+,8+,9-;/m0./s1

Upstream product

• 64-17-5 ethanol 
• 76198-36-2 3-exo-Aminobicyclo<2.2.1>heptane-2-exo-carboxylic Acid 
• 95630-74-3 Ethyl 3-endo-Aminobicyclo<2.2.1>hept-5-ene-2-endo-carboxylate Hydrochloride 
• 53623-52-2 3-endo-Aminobicyclo<2.2.1>hept-5-ene-2-endo-carboxylic Acid 
• 179462-36-3 rac-3-amino-bicyclo[2.2.1]heptane-2-carboxylic acid hydrochloride 
• 874292-70-3 rac-3-aza-tricyclo[4.2.1.0^2,5]nonan-4-one 
• 498-66-8 norbornene 
• 88330-32-9 2,3-diexo-3-aminobicyclo[2.2.1]heptane-2-carboxylic acid 
• 179462-36-3 (±)-cis-3-aminobicyclo[2.2.1]heptane-2-carboxylic acid hydrochloride 
• 498-66-8 norborn-2-ene 
• 7486-95-5 exo-3-azatricyclo<4.2.1.0^2,5>nonan-4-one 

Downstream Products

• 95630-77-6 Ethyl 3-endo-Aminobicyclo<2.2.1>heptane-2-endo-carboxylate 
• 1071520-41-6 (1S,2R,3S,4R)-3-(4-fluoro-benzylamino)-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 1086106-51-5 (1R,2S,7R,8S)-5-(-7-amino-1-methyl-1-oxo-1λ⁶benzo[1,2,4]thiadiazin-3-yl)-3-(4-fluoro-benzyl)-6-hydroxy-3-aza-tricyclo[6.2.1.0^2,7]undec-5-en-4-one 
• 1086106-50-4 (1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-5-(1-methyl-7-nitro-1-oxo-1λ⁶-benzo[1,2,4]thiadiazin-3-yl)-3-aza-tricyclo[6.2.1.0^2,7]undec-5-en-4-one 
• 1086106-48-0 (1S,2R,3S,4R)-3-{(4-fluoro-benzyl)-[2-(1-methyl-7-nitro-1-oxo-1λ⁶-benzo[1,2,4]thiadiazin-3-yl)-acetyl]-amino}-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 1086106-29-7 N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.0^2,7]undec-5-en-5-yl]-1-methyl-1-oxo-1λ⁶-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide 
• 104770-15-2 ((1R,2S,3R,4S)-3-Benzylamino-bicyclo[2.2.1]hept-2-yl)-methanol 
• 104770-23-2 (1S,7R,8S)-3-Benzyl-5-oxa-3-aza-tricyclo[6.2.1.0^2,7]undecane 
• 105786-35-4 (rac-di-exo)-3-amino-bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 1071520-38-1 (1R,2S,3R,4S)-3-ethoxycarbonyl-bicyclo [2.2.1]hept-2-yl-aminium (S)-α-hydroxyphenylacetate 
• 1071517-82-2 (1S,2R,3S,4R)-3-(4-fluoro-benzyl)-6-hydroxy-5-(7-iodo-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)-3-aza-tricyclo[6.2.1.0(2,7)]undec-5-en-4-one 
• 1071517-39-9 N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.0(2,7)]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide 
• 1071520-44-9 (1S,2R,3S,4R)-3-{(4-fluorobenzyl)-[2-(7-methanesulfonylamino-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-yl)acetyl]amino}bicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 1071519-59-9 N-{3-[(1R,2S,7R,8S)-3-(4-fluorobenzyl)-6-hydroxy-4-oxo-3-azatricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-7-yl}methanesulfonamide L-arginine salt 

Relevant academic research and scientific papers

[1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS FOR LOWERING SERUM URIC ACID

The present invention describes [1,2,4]thiadiazine 1,1-dioxide compounds and pharmaceutically acceptable salts thereof, which are useful in lowering serum uric acid in a patient in need thereof comprising administering to the patient a therapeutically or

A METHOD OF INHIBITING HEPATITIS C VIRUS BY COMBINATION OF A 5,6-DIHYDRO-1H-PYRIDIN-2-ONE AND ONE OR MORE ADDITIONAL ANTIVIRAL COMPOUNDS

The invention is directed to a method of treating infections by hepatitis C virus by administering N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1 -dioxo-l,4-dihydro-lλ6- benzo[l,2,4]thiadiazin-7-yl} -methanesulfonamide and one or more additional antiviral compounds or pharmaceutical compositions containing such compounds.

[1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS

The invention is directed to [1,2,4]thiadiazine 1,1-dioxide compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS

The invention is directed to 5,6-dihydro-lH-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

1-METHYL-BENZO[1,2,4]THIADIAZINE 1-OXIDE DERIVATIVES

The invention is directed to 1-methyl-benzo[1,2,4]thiadiazine 1-oxide derivatives and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

Stereochemical Studies, 106. - Saturated Heterocycles, 110. - Synthesis of Methylene-bridged Partially Saturated Quinazolones

With imidates, esters (5-8) of di-endo (1 and 2) and di-exo (3 and 4) norbornane- and norbornene-β-amino acids yield methylene-bridged tetrahydro- (18 and 20) and hexahydro-4-quinazolinones (17 and 19); the reaction of the corresponding carboxamides (9-12

Stereochemical Studies. 81 . Saturated Heterocycles. 69 . Preparation of Methylene-bridged 3,1-Benzoxazines, 3,1-Benzoxazin-2-ones and 3,1-Benzoxazine-2-thiones

3-exo-Aminobicyclohept-5-ene-2-exo-carboxylic acid and ethyl 3-endo-aminobicycloheptane-2-endo-carboxylate (6) were reduced with lithium aluminum hydride to the corresponding bicyclic aminoalcohols 3 and 4.These and the saturated endo-endo a