95639-18-2

Basic information

• Product Name: 1-(benzyloxy)-3-morpholin-4-ylpropan-2-ol
• Synonyms: 1-(Benzyloxy)-3-(morpholin-4-yl)propan-2-ol; 4-Morpholineethanol, alpha-[(phenylmethoxy)methyl]-
• CAS NO: 95639-18-2
• Molecular Formula: C₁₄H₂₁NO₃
• Molecular Weight: 251.3214
• Mol File: 95639-18-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 400.5°C at 760 mmHg
• Flash Point: 196°C
• Density: 1.121g/cm³
• Vapor Pressure: 3.93E-07mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: 1-(benzyloxy)-3-morpholin-4-ylpropan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzyloxy)-3-morpholin-4-ylpropan-2-ol(95639-18-2)
• EPA Substance Registry System: 1-(benzyloxy)-3-morpholin-4-ylpropan-2-ol(95639-18-2)

Safety Data

• Hazardous Substances Data: 95639-18-2(Hazardous Substances Data)

Usage

Physical state

White to off-white solid

Usage

Reagent in organic synthesis

Structural components

Benzyl ether group
Morpholine ring
Propanol group

Industry application

Pharmaceutical industry

Purpose in pharmaceuticals

Building block for the synthesis of various biologically active compounds

Utility

Structure and reactivity useful in the development of new drugs and pharmaceutical products

Upstream product

• 110-91-8 morpholine 
• 13991-52-1 1-chloro-2-hydroxy-3-phenylmethoxypropane 
• 2930-05-4 Benzyloxymethyl-oxiran 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Glycerine and CeClH: An efficient and recyclable reaction medium for ring opening of epoxides with thioamides and amines

Oxiranes undergo rapid ring-opening reaction with a range of thioamides and amines to afford the corresponding -amino alcohol derivatives. The reactions were carried out using glycerine and cerium(III) chloride as a recyclable reaction medium. All the reactions were carried out at room temperature and the products were obtained in excellent yields. Georg Thieme Verlag Stuttgart New York.

SYNTHESIS AND UTEROSTIMULATING ACTIVITY OF DERIVATIVES OF 1-DIALKYLAMINO-3-ALKOXY-2-PROPANOL

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