956431-01-9

Usage

Uses

Used in Organic Synthesis:
4-Formyl-3-methoxyphenylboronic acid pinacol ester is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, which is crucial in creating complex molecular structures with precision and efficiency.
Used in Pharmaceutical Production:
As a valuable building block, 4-Formyl-3-methoxyphenylboronic acid pinacol ester is utilized in the production of pharmaceuticals, contributing to the development of new drug candidates and advancing chemical innovations in the healthcare industry.
Used in Agrochemical Development:
4-Formyl-3-methoxyphenylboronic acid pinacol ester also plays a role in the agrochemical sector, where it is employed as a building block for the synthesis of various agrochemicals, thereby supporting agricultural advancements and crop protection.
Used in Materials Science:
4-Formyl-3-methoxyphenylboronic acid pinacol ester is used as a component in the development of new materials, showcasing its broad applicability across different scientific disciplines and industries.

Upstream product

• 43192-33-2 4-bromo-2-methoxybenzaldehyde 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 73183-34-3 bis(pinacol)diborane 

Relevant academic research and scientific papers

All-Visible-Light-Activated Dithienylethenes Induced by Intramolecular Proton Transfer

The fast light-responsive dithienylethenes (DTEs) are one of the most attractive photochromic families because of their excellent thermal irreversibility and fatigue resistance. However, the all-visible-light-activated DTE system still remains challenging because most of them require the harmful high-energy ultraviolet light to trigger their photocyclization reaction. Here, we have for the first time borrowed a specific intramolecular proton transfer (IPT) process and rationally designed a series of all-visible-light-driven DTEs. Incorporating the IPT-functional group to DTE unit gives rise to an extra absorption band with a distinct red shift, which enables the photocyclization of DTEs under stimuli of visible light at 450 nm, as well as ensuring the desirable photoswitching efficiency. The isomerization from OH form to NH form induced by IPT can decrease the energy gap for excitation and photocyclization, thereby affording the all-visible-light-triggered photochromic performance, which can not only work well in a polar solvent system but also show its effectiveness in polymeric gel systems. In this regard, we can provide a general and reliable platform to construct all-visible-light-driven DTEs with excellent reversible photoswitching and broad applicability, especially with avoiding the use of harmful ultraviolet light to induce their photocyclization.

Piperazine Heteroaryl Derivatives as Gpr38 Agonists

The invention provides compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, Z, X and B are as defined in the specification. The compounds are partial or full agonists at the GPR38 receptor. Pharmaceutical compositions comprising the compounds, methods of preparing the compounds, uses of the compounds and methods involving the compounds are also provided.

A nonacid degradable linker for solid-phase synthesis

Synthesis and applications of two new nonacid degradable linkers as an alternative to the Wang linker for solid-phase synthesis are described. Resin from linker 2 looks superior to linker 1 in terms of yields for both anchoring of the first building block and cleavage and in terms of higher purity of the final product. Use of linker 2 avoids side reactions associated with the use of Wang resin due to an undesired cleavage during final acid treatment.