956474-80-9Relevant academic research and scientific papers
An efficient formal synthesis of (S)-dapoxetine from enantiopure 3-hydroxy azetidin-2-one
Chincholkar, Pinak M.,Kale, Ajaykumar S.,Gumaste, Vikas K.,Deshmukh, Abdul Rakeeb A.S.
scheme or table, p. 2605 - 2609 (2009/08/08)
An efficient formal synthesis of S-(+) dapoxetine starting from 3-hydroxy azetidin-2-one is described. The intermediate (S)-3-(dimethyl amino)-3-phenylpropan-1-ol was synthesized in enantiopure form starting with 3-hydroxy azetidin-2-one in seven steps.
An efficient synthesis of azetidine-2,3-diones from L-(+)-diethyl tartrate
Chincholkar, Pinak M.,Puranik, Vedavati G.,Deshmukh, Abdul Rakeeb A. S.
, p. 2242 - 2246 (2008/02/10)
A convenient route to enantiopure azetidine-2,3-diones is described. The chiral ketene generated from commercially available L-(+)-diethyl tartrate on Staudinger cycloaddition with different imines gave spiro-β-lactams in good yields. These spiro-β-lactam
