95648-10-5 Usage
Uses
Used in Organic Synthesis:
Potassium 1-Hydroxy-4-naphthol Sulfate is used as a synthetic intermediate for the production of various organic compounds. Its unique chemical structure allows it to participate in a range of reactions, making it a valuable component in the synthesis of pharmaceuticals, dyes, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Potassium 1-Hydroxy-4-naphthol Sulfate is used as a key building block in the synthesis of certain drugs. Its reactivity and functional groups enable the creation of new drug molecules with potential therapeutic applications.
Used in Dye Industry:
Potassium 1-Hydroxy-4-naphthol Sulfate is also utilized in the dye industry for the production of colorants and pigments. Its chemical properties contribute to the development of dyes with specific color characteristics and stability.
Used in Research and Development:
In research and development settings, Potassium 1-Hydroxy-4-naphthol Sulfate serves as a valuable compound for exploring new chemical reactions and pathways. Its use in academic and industrial research helps to advance the understanding of organic chemistry and the development of innovative products.
Check Digit Verification of cas no
The CAS Registry Mumber 95648-10-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,6,4 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 95648-10:
(7*9)+(6*5)+(5*6)+(4*4)+(3*8)+(2*1)+(1*0)=165
165 % 10 = 5
So 95648-10-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H8O5S.K/c11-9-5-6-10(15-16(12,13)14)8-4-2-1-3-7(8)9;/h1-6,11H,(H,12,13,14);/q;+1/p-1
95648-10-5Relevant articles and documents
Synthesis of 4'-Hydroxypropranolol Sulfate, a Major Non-β-Blocking Propranolol Metabolite in Man
Oatis, John E.,Walle, T.,Daniell, H. B.,Gaffney, T. E.,Knapp, D. R.
, p. 822 - 824 (1985)
4'-Hydroxypropranolol sulfate (8) was recently identified as a major metabolite of propranolol (Inderal).In order to confirm the structure and to further study disposition and biological activity, he have synthesized 8 with use of 1,4-naphthoquinone (1) as the starting material.Reduction and alkylation with benzyl iodide gave 4-(benzyloxy)naphthol (3).Sulfation and chlorosulfuric acid in N,N-dimethylaniline gave potassium 1-(benzyloxy)-4-naphthol sulfate (4).Catalytic hydrogenation, alkylation with oxy>methyl>oxirane (6), and amination in isopropylamine gave 8.Racemic 8 was found to be 100-1000 times less potent than racemic propranolol as a β-adrenergic receptor blocking agent in the dog.
