95648-12-7 Usage
Uses
Used in Organic Synthesis:
Potassium 1-(2,3-Epoxypropoxy)-4-naphthol Sulfate is used as a key intermediate in the synthesis of various organic compounds. Its epoxypropoxy group allows for the formation of new carbon-carbon bonds, while the naphthol sulfate group provides opportunities for further functionalization and modification of the molecule. This makes it a valuable building block for the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Potassium 1-(2,3-Epoxypropoxy)-4-naphthol Sulfate is used as a starting material for the synthesis of novel drug candidates. Its unique structure can be exploited to design and develop new molecules with potential therapeutic applications, such as antimicrobial, antiviral, or anticancer agents. The versatility of its chemical properties allows for the creation of diverse drug candidates with improved efficacy and selectivity.
Used in Agrochemical Industry:
Potassium 1-(2,3-Epoxypropoxy)-4-naphthol Sulfate is also utilized in the agrochemical industry for the development of new pesticides and herbicides. Its chemical properties can be tailored to target specific pests or weeds, leading to the creation of more effective and environmentally friendly agrochemicals.
Used in Dye and Pigment Industry:
In the dye and pigment industry, Potassium 1-(2,3-Epoxypropoxy)-4-naphthol Sulfate is used as a precursor for the synthesis of various dyes and pigments. Its naphthol structure provides a strong chromophore, which can be further modified to produce a wide range of colors and shades. This makes it suitable for applications in textiles, plastics, and other industries that require colorants.
Used in Polymer Industry:
In the polymer industry, Potassium 1-(2,3-Epoxypropoxy)-4-naphthol Sulfate can be used as a monomer or a comonomer in the synthesis of polymers with specific properties. Its epoxypropoxy group can be polymerized to form polymers with unique mechanical, thermal, and chemical properties, making them suitable for various applications, such as coatings, adhesives, and composite materials.
Check Digit Verification of cas no
The CAS Registry Mumber 95648-12-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,6,4 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 95648-12:
(7*9)+(6*5)+(5*6)+(4*4)+(3*8)+(2*1)+(1*2)=167
167 % 10 = 7
So 95648-12-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H12O6S.K/c14-20(15,16)19-13-6-5-12(18-8-9-7-17-9)10-3-1-2-4-11(10)13;/h1-6,9H,7-8H2,(H,14,15,16);/q;+1/p-1
95648-12-7Relevant academic research and scientific papers
Synthesis of 4'-Hydroxypropranolol Sulfate, a Major Non-β-Blocking Propranolol Metabolite in Man
Oatis, John E.,Walle, T.,Daniell, H. B.,Gaffney, T. E.,Knapp, D. R.
, p. 822 - 824 (2007/10/02)
4'-Hydroxypropranolol sulfate (8) was recently identified as a major metabolite of propranolol (Inderal).In order to confirm the structure and to further study disposition and biological activity, he have synthesized 8 with use of 1,4-naphthoquinone (1) as the starting material.Reduction and alkylation with benzyl iodide gave 4-(benzyloxy)naphthol (3).Sulfation and chlorosulfuric acid in N,N-dimethylaniline gave potassium 1-(benzyloxy)-4-naphthol sulfate (4).Catalytic hydrogenation, alkylation with oxy>methyl>oxirane (6), and amination in isopropylamine gave 8.Racemic 8 was found to be 100-1000 times less potent than racemic propranolol as a β-adrenergic receptor blocking agent in the dog.
