95698-22-9

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 1896-62-4 (E)-benzalacetone 

Downstream Products

• 10346-08-4 3,5-diphenylcyclohex-2-en-1-one 
• 95698-20-7 2-hydroxy-4-oxo-2,6-diphenyl-cyclohexanecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

Indium(III) chloride catalyzed conjugate addition of 1,3-dicarbonyl compounds to α,β-unsaturated ketones

Indium trichloride catalyzes efficiently the Michael reactions of 1,3-dicarbonyl compounds with α,β-unsaturated ketones to afford the corresponding Michael adducts in high yields with high selectivity.

ZrCl4-catalyzed Michael reaction of 1,3-dicarbonyls and enones under solvent-free conditions

ZrCl4 has been found to catalyze the conjugate addition of 1,3-dicarbonyl compounds with enones. The reaction does not require any solvent and proceeds smoothly at room temperature leading to the corresponding adduct in good yields.

Iron(III) catalysis of the Michael reaction of 1,3-dicarbonyl compounds and enones

Iron(III) chloride hexahydrate catalyses the Michael reaction of β-dicarbonyl compounds and enones under mild and neutral conditions with excellent yields and product selectivity.

LITHIUM HYDROXIDE-CATALYZED CONJUGATE ADDITION OF β-DICARBONYL COMPOUNDS

Lithium hydroxide proves to be a very efficient catalyst for Michael addition of β-dicarbonyl compounds 1.The application of the methodology to α,γ-diketo esters and α-keto γ-diesters 4 allows an easy approach to δ-diketones and δ-keto esters 5, respectiv