957127-83-2 Usage
Uses
Used in Organic Synthesis:
N-BOC-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER is used as a building block for the synthesis of biologically active molecules, leveraging its indole core structure and functional groups for the creation of various organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-BOC-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER is used as a precursor in the development of pharmaceuticals, taking advantage of its potential pharmacological activity and the ability to modify its structure for specific therapeutic applications.
Used in Chemical Research:
N-BOC-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER is utilized as a research tool in chemical studies, where its protective N-BOC group and methyl ester functionality are explored for their roles in reaction mechanisms and the synthesis of complex molecules.
Used in Drug Discovery:
In drug discovery processes, N-BOC-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER is employed as a starting material for the design and synthesis of new drug candidates, capitalizing on its adaptability and the possibility of creating molecules with desired biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 957127-83-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,7,1,2 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 957127-83:
(8*9)+(7*5)+(6*7)+(5*1)+(4*2)+(3*7)+(2*8)+(1*3)=202
202 % 10 = 2
So 957127-83-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H17NO4/c1-15(2,3)20-14(18)16-8-7-10-5-6-11(9-12(10)16)13(17)19-4/h5-9H,1-4H3
957127-83-2Relevant articles and documents
Intermodular decarboxylative direct C-3 arylation of indoles with benzoic acids
Cornelia, Josep,Lu, Pengfel,Larrosa, Igor
supporting information; experimental part, p. 5506 - 5509 (2010/02/28)
"Chemical Equation Presented" A palladium catalyzed C-H activation of indoles and a silver catalyzed decarboxylative C-C activation of ortho substituted benzoic acids are synergistically combined to synthesize indoles arylated exclusively In the C-3 posit
Elements of regiocontrol in palladium-catalyzed oxidative arene cross-coupling
Stuart, David R.,Villemure, Elisia,Fagnou, Keith
, p. 12072 - 12073 (2008/03/27)
By changing the stoichiometric oxidant and modifying the indole N-substituent in palladium-catalyzed oxidative arene cross-coupling reactions, both C2 and C3 oxidative indole arylation can be achieved in high yield. High regioselectivity can also be achieved with the benzene component, and the use of this methodology with pyrrole substrates is illustrated. A mechanistic hypothesis for the change in C2/C3 selectivity is advanced. Copyright
