957198-30-0

Basic information

• Product Name: 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
• Synonyms: 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER;2-(4-Morphelino)pyrimidine-5-boronic acid pinacol ester;9 2-(4-Morpholino)pyrimidine-5-boronic acid pinacol ester;2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine;2-Morpholino-4-pyrimidine-5-boronic acid pinacol ester;4-(5-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidin-2-yl)Morpholine;2-(4-Morpholino)pyrimidine-5-boronic acid, pinacol eser
• CAS NO: 957198-30-0
• Molecular Formula: C₁₄H₂₂BN₃O₃
• Molecular Weight: 291.15
• Product Categories: Organoborons;Pyrimidine
• Mol File: 957198-30-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 453.4 °C at 760 mmHg
• Flash Point: 228 °C
• Appearance: /
• Density: 1.16
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER(957198-30-0)
• EPA Substance Registry System: 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER(957198-30-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 957198-30-0(Hazardous Substances Data)

Usage

General Description

The chemical 2-(4-morpholino)pyrimidine-5-boronic acid pinacol ester is an organic compound that contains a boronic acid functional group. It is commonly used in organic synthesis as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, particularly in the field of medicinal chemistry. 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER is often employed in the synthesis of pharmaceuticals and agrochemicals, as well as in the development of new materials. It can also serve as a building block for the preparation of various heterocyclic compounds. Due to its versatile reactivity and potential applications, 2-(4-morpholino)pyrimidine-5-boronic acid pinacol ester is a valuable compound in the field of organic and medicinal chemistry.

Upstream product

• 84539-22-0 4-(5-bromopyrimidin-2-yl)morpholine 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1253936-70-7 1-{4-[2-(2-morpholin-4-yl-pyrimidin-5-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl}-2-pyrrolo[2,3-b]pyridin-1-yl-ethanone 
• 1253936-96-7 1-{4-[2-(2-morpholin-4-yl-pyrimidin-5-yl)phenyl]piperidin-1-yl}-2-pyrrolo[2,3-b]pyridin-1-yl-ethanone 
• 1253936-68-3 4-[2-(2-morpholin-4-yl-pyrimidin-5-yl)phenyl]-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 1253936-69-4 4-{5-[2-(1,2,3,6-tetrahydro-pyridin-4-yl)phenyl]pyrimidin-2-yl}morpholine 
• 1400754-84-8 {3-[2-(morpholin-4-yl)pyrimidin-5-yl]phenyl}methanol 
• 1279028-30-6 tert-butyl [2-(methyl{3-[2-(morpholin-4-yl)pyrimidin-5-yl]benzyl}amino)-2-oxoethyl]carbamate 

Relevant articles and documents

1,5,7-TRISUBSTITUTED ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES

The present disclosure relates to 1,5,7-trisubstituted isoquinoline derivatives, their preparation and pharmaceutical use. In particular, the present disclosure discloses a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, and a preparation method and use thereof. The definitions of the groups in the formula can be found in the specification and claims.

HETEROARYL COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF

The present invention provides herein is a heteroaryl compound or a stereoisomer, a geometric isomer, a tautomer, a racemate, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, as well as a pharmaceutical composition containing the compound disclosed herein. The present invention also provides herein is use of the compound or the pharmaceutical composition thereof disclosed herein in the manufacture of a medicine for treating autoimmune diseases or proliferative diseases.