957214-73-2Relevant academic research and scientific papers
Synthesis of diverse heterocyclic scaffolds via tandem additions to imine derivatives and ring-forming reactions
Sunderhaus, James D.,Dockendorff, Chris,Martin, Stephen F.
experimental part, p. 6454 - 6469 (2011/02/26)
A novel strategy has been developed for the efficient syntheses of diverse arrays of heterocyclic compounds. The key elements of the approach comprise a Mannich-type, multicomponent coupling reaction in which functionalized amines, aromatic aldehydes, acy
Applications of multicomponent reactions for the synthesis of diverse heterocyclic scaffolds
Sunderhaus, James D.,Dockendorff, Chris,Martin, Stephen F.
, p. 4223 - 4226 (2008/02/12)
A four-component coupling process involving sequential reactions of aldehydes, primary amines, acid chlorides, and nucleophiles has been developed to prepare multifunctional substrates that may be employed in subsequent ring-forming reactions to generate
