95734-31-9Relevant articles and documents
Amide/Ester Cross-Coupling via C-N/C-H Bond Cleavage: Synthesis of β-Ketoesters
Chen, Jiajia,Joseph, Devaneyan,Xia, Yuanzhi,Lee, Sunwoo
, p. 5943 - 5953 (2021/04/02)
Activated primary, secondary, and tertiary amides were coupled with enolizable esters in the presence of LiHMDS to obtain good yields of β-ketoesters at room temperature. Notably, this protocol provides an efficient, mild, and high chemoselectivity method
Bronsted base-catalyzed tandem isomerization-Michael reactions of alkynes: Synthesis of oxacycles and azacycles
Liu, Hongjun,Feng, Wei,Kee, Choon Wee,Leow, Dasheng,Loh, Wei-Tian,Tan, Choon-Hong
supporting information; experimental part, p. 3373 - 3379 (2011/02/28)
An efficient synthesis of oxacycles and azacycles was developed using a Bronsted base-catalyzed tandem alkyne isomerization-Michael reaction sequence. Functionalized 2-alkylidenetetrahydrofurans were prepared by an intramolecular oxy-Michael reaction on a
Thiazole and oxazole derivatives as activators of human peroxisome proliferator activated receptors
-
, (2008/06/13)
The present invention provides a compound of formula (1) wherein R1-R5, R25, R26, Y and X2 are defined as in claim 1. The compounds activate human peroxisome proliferator activated receptors (hPPARs) and arc useful for the treatment of associated disorders such as cardiovascular disease and hypercholesteremia.
