957470-59-6Relevant articles and documents
Preparation method of pantoprazole impurity
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Paragraph 0048; 0058-0059; 0060; 0070-0071; 0072; 0082-0083, (2021/05/12)
The invention discloses a preparation method of a pantoprazole impurity. The preparation method is characterized in that 4-difluoromethoxy-2-nitroaniline is used as a raw material, and the synthesis of the pantoprazole impurity is realized through five steps of reactions. The preparation method is reasonable in process design and high in operability, and can realize industrial production; and the prepared pantoprazole impurity is high in purity, and an important basis is provided for scientific evaluation of quality, safety and efficiency of pantoprazole.