957791-72-9

Basic information

• Product Name: (3R,4S)-3-(tert-butyldimethylsilanyloxy)-4-(1-formyl-1,1-dimethylmethyl)-1-(4-methoxyphenyl)azetidin-2-one
• Synonyms: (3R,4S)-3-(tert-butyldimethylsilanyloxy)-4-(1-formyl-1,1-dimethylmethyl)-1-(4-methoxyphenyl)azetidin-2-one
• CAS NO: 957791-72-9
• Molecular Weight: 377.556
• Mol File: 957791-72-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4S)-3-(tert-butyldimethylsilanyloxy)-4-(1-formyl-1,1-dimethylmethyl)-1-(4-methoxyphenyl)azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S)-3-(tert-butyldimethylsilanyloxy)-4-(1-formyl-1,1-dimethylmethyl)-1-(4-methoxyphenyl)azetidin-2-one(957791-72-9)
• EPA Substance Registry System: (3R,4S)-3-(tert-butyldimethylsilanyloxy)-4-(1-formyl-1,1-dimethylmethyl)-1-(4-methoxyphenyl)azetidin-2-one(957791-72-9)

Safety Data

• Hazardous Substances Data: 957791-72-9(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 38216-93-2 3-benzyloxypivalic aldehyde 
• 66582-32-9 3-(benzyloxy)-2,2-dimethylpropan-1-ol 
• 776-88-5 5,5-dimethyl-2-phenyl-[1,3]dioxane 
• 957791-68-3 (3R,4S)-4-(2-benzyloxy-1,1-dimethylethyl)-3-(tert-butyldimethylsilanyloxy)-1-(4-methoxyphenyl)azetidin-2-one 
• 865154-54-7 (3R,4S)-3-hydroxy-4-(2-benzyloxy-1,1-dimethylethyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 957791-46-7 (3R,4S)-3-acetoxy-4-(2-benzyloxy-1,1-dimethylethyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 957791-54-7 (E)-N-(3-(benzyloxy)-2,2-dimethylpropylidene)-4-methoxybenzenamine 
• 957791-70-7 (3R,4S)-3-(tert-butyldimethylsilanyloxy)-4-(1,1-dimethyl-2-hydroxy-ethyl)-1-(4-methoxyphenyl)azetidin-2-one 

Relevant articles and documents

Approaches to the synthesis of enantiopure α-hydroxy-β-lactams with functionalized side chains

We report a synthesis of pharmaceutically important α-hydroxy (or t-butyldimethylsilyl protected α-hydroxy)-β-lactams with functionalized chains in position 4 of the azetidinone ring. A convenient and high-yielding route to these compounds was developed and optimized. Preparation and characterization of several new enantiopure title compounds with various functional groups are discussed.