95811-61-3Relevant academic research and scientific papers
Silver-mediated radical cyclization of alkynoates and α-keto acids leading to coumarins via cascade double c-c bond formation
Yan, Kelu,Yang, Daoshan,Wei, Wei,Wang, Fen,Shuai, Yuanyuan,Li, Qiannan,Wang, Hua
, p. 1550 - 1556 (2015)
A novel and convenient silver-mediated radical cyclization method for the synthesis of coumarin derivatives via the direct difunctionalization of alkynoates with α-keto acids through double C-C bond formation under mild conditions has been developed. This new method is highly efficient and practical, and the starting materials are readily prepared. The present method should provide a useful strategy for the construction of coumarin motifs.
Visible-light-mediated cascade difunctionalization/cyclization of alkynoates with acyl chlorides for synthesis of 3-acylcoumarins
Liu, Yu,Wang, Qiao-Lin,Zhou, Cong-Shan,Xiong, Bi-Quan,Zhang, Pan-Liang,Kang, Shuang-Jian,Yang, Chang-An,Tang, Ke-Wen
supporting information, p. 2038 - 2041 (2018/05/04)
A new visible-light-mediated radical cyclization of alkynoates with acyl chlorides is described for the one-pot construction of diverse 3-acylcoumarins with high efficiency and selectivity. This method is successful by sequential difunctionalization of an alkynes C–C triple bond with the C–Cl bonds of acyl chloride and aromatic C(sp2)–H bonds. The cyclization is proposed to simultaneously form two new carbon–carbon bonds, and involves radical acylation, 5-exo-trig cyclization, and ester migration.
Visible Light-Induced Decarboxylative Acylarylation of Phenyl Propiolates with α-Oxocarboxylic Acids to Coumarins Catalyzed by Hypervalent Iodine Reagents under Transition Metal-Free Conditions
Yang, Shuai,Tan, Hui,Ji, Wangqin,Zhang, Xiangbiao,Li, Pinhua,Wang, Lei
, p. 443 - 453 (2017/02/10)
No Abstract. (Figure presented.).
