95821-72-0

Basic information

• Product Name: C₂₅H₂₉O₅P
• Synonyms: C₂₅H₂₉O₅P
• CAS NO: 95821-72-0
• Molecular Weight: 440.476
• Mol File: 95821-72-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₉O₅P(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₉O₅P(95821-72-0)
• EPA Substance Registry System: C₂₅H₂₉O₅P(95821-72-0)

Safety Data

• Hazardous Substances Data: 95821-72-0(Hazardous Substances Data)

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 122-52-1 triethyl phosphite 
• 40615-35-8 4,4'-dimethoxytrityl alcohol 
• 762-04-9 phosphonic acid diethyl ester 

Relevant articles and documents

A highly efficient nucleophilic substitution reaction between R2P(O)H and triarylmethanols to synthesize phosphorus-substituted triarylmethanes

A highly efficient and general nucleophilic substitution reaction between dialkyl H-phosphonates or diarylphosphine oxides and triarylmethanols catalyzed by HOTf (trifluoromethanesulfonic acid) has been developed. It provides an atom-economical protocol for the synthesis of various symmetrical and unsymmetrical phosphorus-substituted triarylmethanes that constitute an emerging family of potent anticancer agents in rich diversity with 40 to 96% yields. The synthetic applicability of this protocol is demonstrated by gram-scale preparations.