958233-17-5Relevant articles and documents
Radioactive molecular probe taking TSPO as target point as well as preparation method and application thereof
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, (2020/05/30)
The invention discloses a small molecular organic compound with a specific targeting TSPO (Transfer Protein). The structure of the small molecular organic compound comprises a benzene ring, pyrazolo imidazole and a diethyl acetamide structure. The P-tolue
Microwave-assisted organic synthesis of a high-affinity pyrazolo-pyrimidinyl TSPO ligand
Tang, Dewei,Buck, Jason R.,Hight, Matthew R.,Manning, H. Charles
supporting information; experimental part, p. 4595 - 4598 (2010/09/18)
We herein report a dramatically improved total synthesis of the high-affinity translocator protein (TSPO) ligand DPA-714, featuring microwave-assisted organic synthesis (MAOS). Compared with previously described approaches, our novel MAOS method dramatica
Radiosynthesis of [18F]DPA-714, a selective radioligand for imaging the translocator protein (18 kDa) with PET
Damont, Annelaure,Hinnen, Francoise,Kuhnast, Bertrand,Schoellhorn-Peyronneau, Marie-Anne,James, Michelle,Luus, Christopher,Tavitian, Bertrand,Kassiou, Michael,Dolle, Frederic
, p. 286 - 292 (2008/12/22)
Recently, a novel series of 2-phenylpyrazolo[1,5-α] pyrimidineacetamides has been reported as selective ligands of the translocator protein (18 kDa). Within this series, DPA-714 (N,N-diethyl-2-(2-(4-(2- fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-α]pyri